Striker Byron Moore picked up a hamstring injury during Plymouth Argyle’s 2-2 draw away to Crawley Town, manager Ryan Lowe has confirmed.
Moore had to be substituted in the 68th minute of the League Two encounter in West Sussex on Tuesday night.
The severity of the damage done by the speedy 31-year-old attacker will be assessed over the coming days.
Moore missed four matches earlier this season because of a hamstring injury which he suffered in training.
Now, he could be set for another frustrating lay-off after his latest setback.
When Lowe was asked about the injury to Moore after the game against Crawley, he replied: “We will have to assess it tomorrow.
“He’s feeling his hamstring a little bit, but that’s what happens. He has now played two games in four days.”
Moore had to play catch-up over his fitness after signing for Argyle from Bury late into pre-season, and then again after his injury last month.
Lowe said: “We have started doing a little bit more pace and power with him in training because he doesn't get out of second gear, Byron, really until he is motoring like that.
“We will have him addressed, we will look at him and then we will see how he is.
“He has gone right down so I would like to think that if he has done anything it’s hopefully minimal because we got him off the pitch.”
Lowe also reported that midfielder Jose Baxter had been taken off later in the second half due to cramp.
Moore started the game in attack with Joel Grant, who played for the first time since he suffered a hamstring injury on August 10.
Grant played for 89 minutes of his comeback match before making way for on-loan Glasgow Rangers striker Zak Rudden.
Lowe said: “Joel gets hold of the ball, he can twist, he can turn, he makes clever runs. He’s clever on the ball.
“For his size and stature, he’s quite strong. He takes the ball in well and looks after it.
“He’s disappointed he never got a goal or two himself but, again, that’s what we have got, we have got quality players, especially in the attacking half.
“All we are missing now is just one or two of them start knocking some balls in the net.
“That’s what they have got to do, they know that, they understand that, but Joel was fantastic.”
Defender Will Aimson, another of Lowe’s summer signings from Bury, finally made his league debut for Argyle against Crawley.
He missed all of pre-season and the start of the league campaign due to a pelvic problem, but has been training for some time now.
Aimson proved his fitness by playing the whole game against Crawley and he almost marked the occasion with a couple of goals.
The 25-year-old had two excellent shooting opportunities, one in each half, with the second one producing an incredible reflex save from Crawley man-of-the-match Glenn Morris.
Lowe was delighted with the defensive contribution of Aimson too, and thought he had deserved a goal for his efforts.
He said: “He was outstanding weren’t he? I don’t like to single any individual out, but we know what we have got with Will.
“He was just unfortunate not to get a goal. He’s not happy the ‘keeper has made a worldy save.”